Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells

Summary: Enteroviruses, particularly the group B coxsackieviruses (CVBs), have been associated with the development of type 1 diabetes. Several CVB serotypes establish chronic infections in human cells in vivo and in vitro. However, the mechanisms leading to enterovirus persistency and, possibly, be...

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Main Authors: Tanja Buchacher, Anni Honkimaa, Tommi Välikangas, Niina Lietzén, M. Karoliina Hirvonen, Jutta E. Laiho, Amir-Babak Sioofy-Khojine, Eeva-Liisa Eskelinen, Heikki Hyöty, Laura L. Elo, Riitta Lahesmaa
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221016230