Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells

Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells

Summary: Enteroviruses, particularly the group B coxsackieviruses (CVBs), have been associated with the development of type 1 diabetes. Several CVB serotypes establish chronic infections in human cells in vivo and in vitro. However, the mechanisms leading to enterovirus persistency and, possibly, be...

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Bibliographic Details
Main Authors: Tanja Buchacher, Anni Honkimaa, Tommi Välikangas, Niina Lietzén, M. Karoliina Hirvonen, Jutta E. Laiho, Amir-Babak Sioofy-Khojine, Eeva-Liisa Eskelinen, Heikki Hyöty, Laura L. Elo, Riitta Lahesmaa
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Virology
Cell biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221016230

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