Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior
Autism spectrum disorders (ASDs) are associated with mutations affecting synaptic components, including GluN2B-NMDA receptors (NMDARs) and neurobeachin (NBEA). NBEA participates in biosynthetic pathways to regulate synapse receptor targeting, synaptic function, cognition, and social behavior. Howeve...
Main Authors: | Kira V. Gromova, Mary Muhia, Nicola Rothammer, Christine E. Gee, Edda Thies, Irina Schaefer, Sabrina Kress, Manfred W. Kilimann, Olga Shevchuk, Thomas G. Oertner, Matthias Kneussel |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-05-01
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Series: | Cell Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124718307125 |
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