Conformational Landscapes of Halohydrin Dehalogenases and Their Accessible Active Site Tunnels

Halohydrin dehalogenases (HHDH) are industrially relevant biocatalysts exhibiting a promiscuous epoxide-ring opening reactivity in the presence of small nucleophiles, thus giving access to novel carbon–carbon, carbon–oxygen, carbon–nitrogen, and carbon–sulfur bonds. Recently, the repertoire of HHDH...

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Bibliographic Details
Main Authors: Miquel Estévez-Gay, Javier Iglesias-Fernández, Sílvia Osuna
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Catalysts
Subjects:
Online Access:https://www.mdpi.com/2073-4344/10/12/1403