The NS1 protein of the parvovirus MVM Aids in the localization of the viral genome to cellular sites of DNA damage.

The autonomous parvovirus Minute Virus of Mice (MVM) localizes to cellular DNA damage sites to establish and sustain viral replication centers, which can be visualized by focal deposition of the essential MVM non-structural phosphoprotein NS1. How such foci are established remains unknown. Here, we...

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Bibliographic Details
Main Authors: Kinjal Majumder, Maria Boftsi, Fawn B Whittle, Juexin Wang, Matthew S Fuller, Trupti Joshi, David J Pintel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009002