Electroacupuncture attenuates ketamine-induced neuronal injury in the locus coeruleus of rats through modulation of the CAMK II/CREB pathway

Electroacupuncture attenuates ketamine-induced neuronal injury in the locus coeruleus of rats through modulation of the CAMK II/CREB pathway

Background: Ketamine, despite its efficacy in treating depression, raises concerns regarding safety due to potential abuse, cognitive impairment, and bladder toxicity. Ketamine can affect the locus coeruleus (LC) norepinephrine and attention networks. This study explored the protective effects of el...

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Bibliographic Details
Main Authors: Huachun Miao, Runzhi Li, Wenjuan Li, Feng Wu, Huaibin Li, Hong Luo
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Brain Research Bulletin
Subjects:
Ketamine
Locus coeruleus
Electroacupuncture
CAMK II
CREB
P-CREB
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923023001491

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http://www.sciencedirect.com/science/article/pii/S0361923023001491

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