An amino acid substitution in HCV core antigen limits its use as a reliable measure of HCV infection compared with HCV RNA

Hepatitis C virus (HCV) is a viral pathogen that causes chronic hepatitis, which can lead to cirrhosis and hepatocellular carcinoma. Detection of HCV RNA is the standard method used to diagnose the disease and monitor antiviral treatment. A quantification assay for the HCV core antigen (HCVcAg) has...

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Bibliographic Details
Main Authors: Payuda Hansoongnern, Pornpitra Pratedrat, Pornjarim Nilyanimit, Rujipat Wasitthankasem, Nawarat Posuwan, Nasamon Wanlapakorn, Kanchanok Kodchakorn, Prachya Kongtawelert, Napaporn Pimsing, Yong Poovorawan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10310030/?tool=EBI