Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia
Strategies that promote selective activation of prodrugs by enzymes can be divided into two major classes: 1) deliver of a monoclonal antibody-enzyme immunoconjugate that can recognize a specific antigen and promote the prodrug to a citotoxic drug, with a high selectivity for the target cells, and 2...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Química
2006-12-01
|
Series: | Química Nova |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422006000600028&lng=en&tlng=en |