Computational Prediction and Experimental Validation of the Unique Molecular Mode of Action of Scoulerine

Computational Prediction and Experimental Validation of the Unique Molecular Mode of Action of Scoulerine

Scoulerine is a natural compound that is known to bind to tubulin and has anti-mitotic properties demonstrated in various cancer cells. Its molecular mode of action has not been precisely known. In this work, we perform computational prediction and experimental validation of the mode of action of sc...

Full description

Bibliographic Details
Main Authors: Mahshad Moshari, Qian Wang, Marek Michalak, Mariusz Klobukowski, Jack Adam Tuszynski
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
scoulerine
microtubule
cancer treatment
drug discovery
protein docking
molecular dynamic simulation
Online Access:https://www.mdpi.com/1420-3049/27/13/3991

Internet

https://www.mdpi.com/1420-3049/27/13/3991

Similar Items