BTK Inhibitors Impair Platelet-Mediated Antifungal Activity

BTK Inhibitors Impair Platelet-Mediated Antifungal Activity

In recent years, the introduction of new drugs targeting Bruton’s tyrosine kinase (BTK) has allowed dramatic improvement in the prognosis of patients with chronic lymphocytic leukemia (CLL) and other B-cell neoplasms. Although these small molecules were initially considered less immunosuppressive th...

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Bibliographic Details
Main Authors: Vincenzo Nasillo, Ivana Lagreca, Daniela Vallerini, Patrizia Barozzi, Giovanni Riva, Monica Maccaferri, Ambra Paolini, Fabio Forghieri, Stefania Fiorcari, Rossana Maffei, Silvia Martinelli, Claudio Giacinto Atene, Ilaria Castelli, Roberto Marasca, Leonardo Potenza, Patrizia Comoli, Rossella Manfredini, Enrico Tagliafico, Tommaso Trenti, Mario Luppi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cells
Subjects:
BTK inhibitors
platelets
ibrutinib
acalabrutinib
CLL
invasive fungal infections
Online Access:https://www.mdpi.com/2073-4409/11/6/1003

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https://www.mdpi.com/2073-4409/11/6/1003

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