Utility of Next-Generation Sequencing in the Reconstruction of Clonal Architecture in a Patient with an <i>EGFR</i> Mutated Advanced Non-Small Cell Lung Cancer: A Case Report
EGFR tyrosine kinase inhibitors (EGFR-TKIs) have revolutionized the treatment of non-small cell lung cancer (NSCLC) patients with activating <i>EGFR</i> mutations. However, targeted therapies impose a strong selective pressure against the coexisting tumor populations that lead to the eme...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-05-01
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Series: | Diagnostics |
Subjects: | |
Online Access: | https://www.mdpi.com/2075-4418/12/5/1266 |