The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype

The role of vimentin in the tumor marker Nup88-dependent multinucleated phenotype

Abstract Background Nucleoporin Nup88, a component of nuclear pore complexes, is known to be overexpressed in several types of tumor tissue. The overexpression of Nup88 has been reported to promote the early step of tumorigenesis by inducing multinuclei in both HeLa cells and a mouse model. However,...

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Bibliographic Details
Main Authors: Masaki Makise, Hideaki Nakamura, Akihiko Kuniyasu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Nup88
Nucleoporin
Vimentin
Cancer
Multinucleated phenotype
Kinases
Online Access:http://link.springer.com/article/10.1186/s12885-018-4454-y

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http://link.springer.com/article/10.1186/s12885-018-4454-y

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