Tetrandrine induces muscle atrophy involving ROS-mediated inhibition of Akt and FoxO3

Abstract Tetrandrine (Tet), a well-known drug of calcium channel blocker, has been broadly applied for anti-inflammatory and anti-fibrogenetic therapy. However, due to the functional diversity of ubiquitous calcium channels, potential side-effects may be expected. Our previous report revealed an inh...

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Bibliographic Details
Main Authors: Xin-qi Shan, Na Zhou, Chuang-xin Pei, Xue Lu, Cai-ping Chen, Hua-qun Chen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-024-00981-x