The CIt protocol: A blueprint to potentiate the immunogenicity of immunoproteasome-reprogrammed mesenchymal stromal cells

Summary: Immunoproteasome-reprogrammed mesenchymal stromal cells (IRMs) can surpass dendritic cells at eliciting tumor-specific immunity. However, the current IRM vaccination regimen remains clinically unsuitable due to the relatively high dose of IRMs needed. Since the administration of a lower IRM...

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Bibliographic Details
Main Authors: Jean-Pierre Bikorimana, Nehme El-Hachem, Jamilah Abusarah, Nicoletta Eliopoulos, Sebastien Talbot, Riam Shammaa, Moutih Rafei
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222018090