Glycosylated Flavonoid Compounds as Potent CYP121 Inhibitors of <i>Mycobacterium tuberculosis</i>

Glycosylated Flavonoid Compounds as Potent CYP121 Inhibitors of <i>Mycobacterium tuberculosis</i>

Due to the concerning rise in the number of multiple- and prolonged-drug-resistant (MDR and XDR) <i>Mycobacterium tuberculosis</i> (Mtb) strains, unprecedented demand has been created to design and develop novel therapeutic drugs with higher efficacy and safety. In this study, with a foc...

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Bibliographic Details
Main Authors: Leena Hussein Bajrai, Aiah M. Khateb, Maha M. Alawi, Hashim R. Felemban, Anees A. Sindi, Vivek Dhar Dwivedi, Esam Ibraheem Azhar
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
CYP121
<i>Mycobacterium tuberculosis</i>
protein-ligand interaction
docking
molecular dynamic simulation
Online Access:https://www.mdpi.com/2218-273X/12/10/1356

Internet

https://www.mdpi.com/2218-273X/12/10/1356

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