Steatosis and Metabolic Disorders Associated with Synergistic Activation of the CAR/RXR Heterodimer by Pesticides

Steatosis and Metabolic Disorders Associated with Synergistic Activation of the CAR/RXR Heterodimer by Pesticides

The nuclear receptor, constitutive androstane receptor (CAR), which forms a heterodimer with the retinoid X receptor (RXR), was initially reported as a transcription factor that regulates hepatic genes involved in detoxication and energy metabolism. Different studies have shown that CAR activation r...

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Bibliographic Details
Main Authors: Yannick Dauwe, Lucile Mary, Fabiana Oliviero, Marina Grimaldi, Patrick Balaguer, Véronique Gayrard, Laïla Mselli-Lakhal
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
CAR
RXR
nuclear
receptor
pesticides
steatosis
Online Access:https://www.mdpi.com/2073-4409/12/8/1201

Internet

https://www.mdpi.com/2073-4409/12/8/1201

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