Reference Values to Assess Hemodilution and Warn of Potential False-Negative Minimal Residual Disease Results in Myeloma

Background: Whereas, in most patients with multiple myeloma (MM), achieving undetectable MRD anticipates a favorable outcome, some others relapse shortly afterwards. Although one obvious explanation for this inconsistency is the use of nonrepresentative marrow samples due to hemodilution, there is n...

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Main Authors: Noemí Puig, Juan Flores-Montero, Leire Burgos, María-Teresa Cedena, Lourdes Cordón, José-Juan Pérez, Luzalba Sanoja-Flores, Irene Manrique, Paula Rodríguez-Otero, Laura Rosiñol, Joaquín Martínez-López, María-Victoria Mateos, Juan-José Lahuerta, Joan Bladé, Jesús F. San Miguel, Alberto Orfao, Bruno Paiva
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/19/4924