The mitochondrial DNA common deletion as a potential biomarker of cancer-associated fibroblasts from skin basal and squamous cell carcinomas

Abstract Cancer-associated fibroblasts (CAFs) are components of the tumor microenvironment and represent appealing therapeutic targets for translational studies. Conventional protein-based biomarkers for CAFs have been reported to be limited in their specificity, rendering difficult the identificati...

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Bibliographic Details
Main Authors: Gabriele A. Fontana, Michael R. MacArthur, Nadezhda Rotankova, Michela Di Filippo, Hans-Dietmar Beer, Hailey L. Gahlon
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50213-1