Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of fibromodulin

Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of fibromodulin

Abstract Neointimal hyperplasia is a pathological vascular remodeling caused by abnormal proliferation and migration of subintimal vascular smooth muscle cells (VSMCs) following intimal injury. There is increasing evidence that tRNA-derived small RNA (tsRNA) plays an important role in vascular remod...

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Bibliographic Details
Main Authors: Qi-Lan Jiang, Jia-Ying Xu, Qing-Ping Yao, Rui Jiang, Qin Xu, Bo-Tao Zhang, Tao Li, Jun Jiang
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cellular & Molecular Biology Letters
Subjects:
Transfer RNA (tRNA)-derived small RNAs (tsRNAs)
Vascular smooth muscle cell
Vascular remodeling
Neointimal hyperplasia (NIH)
Proliferation
Migration
Online Access:https://doi.org/10.1186/s11658-023-00523-z

Internet

https://doi.org/10.1186/s11658-023-00523-z

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