Gender-Specific Adverse Effects of Mono-ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig Cell Progenitors in vitro

Gender-Specific Adverse Effects of Mono-ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig Cell Progenitors in vitro

Di-2-ethylhexyl (DEHP) phthalate, one of the phthalates most widely distributed in the environment, causes reproductive toxicity that is attributable to the action of its primary metabolite, mono (2-ethylhexyl) phthalate (MEHP). Here, we have investigated the effects of MEHP on steroidogenesis by pr...

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Bibliographic Details
Main Authors: Konstantin eSvechnikov, Irina eSvechnikova, Olle eSoder
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-04-01
Series:Frontiers in Endocrinology
Subjects:
immature granulosa cells
mono-ethylhexyl phthalate
progenitor Leydig cells
steroidogenesis
steroidogenic acute regulatory protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00009/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00009/full

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