Blockade of AMPK-Mediated cAMP–PKA–CREB/ATF1 Signaling Synergizes with Aspirin to Inhibit Hepatocellular Carcinoma

Aspirin can prevent or inhibit inflammation-related cancers, such as colorectal cancer and hepatocellular carcinoma (HCC). However, the effectiveness of chemotherapy may be compromised by activating oncogenic pathways in cancer cells. Elucidation of such chemoresistance mechanisms is crucial to deve...

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Bibliographic Details
Main Authors: Hongying Zhang, Songpeng Yang, Jiao Wang, Yangfu Jiang
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/7/1738