The Effect of Ethanol on Disassembly of Amyloid-β<sub>1-42</sub> Pentamer Revealed by Atomic Force Microscopy and Gel Electrophoresis

The Effect of Ethanol on Disassembly of Amyloid-β<sub>1-42</sub> Pentamer Revealed by Atomic Force Microscopy and Gel Electrophoresis

The most common type of dementia, Alzheimer’s disease, is associated with senile plaques formed by the filamentous aggregation of hydrophobic amyloid-β (Aβ) in the brains of patients. Small oligomeric assemblies also occur and drugs and chemical compounds that can interact with such assemblies have...

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Bibliographic Details
Main Authors: Atsuya Matsui, Jean-Pierre Bellier, Takeshi Kanai, Hiroki Satooka, Akio Nakanishi, Tsukasa Terada, Takafumi Ishibe, Yoshiaki Nakamura, Hiroyasu Taguchi, Nobuyasu Naruse, Yutaka Mera
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
amyloid-β
oligomer
atomic force microscopy
gel electrophoresis
Gaussian fitting
Online Access:https://www.mdpi.com/1422-0067/23/2/889

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https://www.mdpi.com/1422-0067/23/2/889

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