Histone Marks-Dependent Effect on Alternative Splicing: New Perspectives for Targeted Splicing Modulation in Cancer?
Alternative splicing (AS) is a tightly regulated mechanism that generates the complex human proteome from a small number of genes. <i>Cis</i>-regulatory RNA motifs in exons and introns control AS, recruiting positive and negative <i>trans</i>-acting splicing regulators. At a...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/23/15/8304 |