Myeloperoxidase and Other Markers of Neutrophil Activation Associate With Malaria and Malaria/HIV Coinfection in the Human Placenta

Myeloperoxidase and Other Markers of Neutrophil Activation Associate With Malaria and Malaria/HIV Coinfection in the Human Placenta

IntroductionPlacental malaria (PM) is characterized by accumulation of inflammatory leukocytes in the placenta, leading to poor pregnancy outcomes. Understanding of the underlying mechanisms remains incomplete. Neutrophils respond to malaria parasites by phagocytosis, generation of oxidants, and ext...

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Bibliographic Details
Main Authors: Demba Sarr, Lilian J. Oliveira, Brittany N. Russ, Simon O. Owino, Joab D. Middii, Stephen Mwalimu, Linda Ambasa, Faris Almutairi, John Vulule, Balázs Rada, Julie M. Moore
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
neutrophils
pregnancy
NETs (neutrophil extracellular traps)
placental malaria
myeloperoxidase
Plasmodium falciparum
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.682668/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.682668/full

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