Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia

Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia

Abstract Background Cachexia frequently occurs in women with advanced ovarian cancer (OC), along with enhanced inflammation. Despite being responsible for one third of all cancer deaths, cachexia is generally under‐studied in OC due to a limited number of pre‐clinical animal models. We aimed to addr...

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Bibliographic Details
Main Authors: Fabrizio Pin, Rafael Barreto, Yukiko Kitase, Sumegha Mitra, Carlie E. Erne, Leah J. Novinger, Teresa A. Zimmers, Marion E. Couch, Lynda F. Bonewald, Andrea Bonetto
Format: Article
Language:English
Published: Wiley 2018-08-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Cancer cachexia
Ovarian cancer
Skeletal muscle
Animal model
ES‐2
IL‐6
Online Access:https://doi.org/10.1002/jcsm.12311

Internet

https://doi.org/10.1002/jcsm.12311

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