Minocycline relieves neuropathic pain in rats with spinal cord injury via activation of autophagy and suppression of PI3K/Akt/mTOR pathway
Objective: In this study, we studied whether minocycline hydrochloride improved neuropathic pain induced by spinal cord injury (SCI) in rats through PI3K/Akt pathway. Methods: The SCI was induced by compressed at level of T9-T11 of spinal cord in Sprague Dawley male rats. Animals were given differen...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | Journal of Pharmacological Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861323000361 |