CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway

CD5L deficiency attenuate acetaminophen-induced liver damage in mice via regulation of JNK and ERK signaling pathway

Abstract CD5 molecule like (CD5L), a member of the scavenger receptor cysteine-rich domain superfamily, plays a critical role in immune homeostasis and inflammatory disease. Acetaminophen (APAP) is a safe and effective antipyretic analgesic. However, overdose may cause liver damage or even liver fai...

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Bibliographic Details
Main Authors: Mengjing Li, Tao Ling, Fengmeng Teng, Chao Hu, Zhongping Su, Chen Zhang, Xiang Li, Ting Zhao, Xianmin Mu, Yingchang Li, Jinshun Pan, Qiang You
Format: Article
Language:English
Published: Nature Publishing Group 2021-11-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00742-3

Internet

https://doi.org/10.1038/s41420-021-00742-3

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