Let-7a Inhibits T-Cell Proliferation and IFN-γ Secretion by Down-Regulating STAT3 Expression in Patients with Psoriasis

Let-7a Inhibits T-Cell Proliferation and IFN-γ Secretion by Down-Regulating STAT3 Expression in Patients with Psoriasis

Objective: This study aimed to explore the effects of STAT3 targeting by let-7a on T-cell proliferation and IFN-γ secretion in psoriasis. Methods: From January 2013 to January 2015, 40 patients with psoriasis (psoriasis group) and 38 volunteers undergoing plastic surgery (control group) were enrolle...

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Bibliographic Details
Main Authors: Xiao-Ping Hu, Qian Xie, Chao-Feng Chen, Wei Zhang, Bo Yu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Psoriasis
Let-7a
STAT3
Interferon-γ
T-cell
Proliferation
Online Access:http://www.karger.com/Article/FullText/477120

Internet

http://www.karger.com/Article/FullText/477120

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