Heparin in Acid and Alkaline Environments—A Study of the Correlations between Hydrodynamic Properties and Desulphation

Heparin in Acid and Alkaline Environments—A Study of the Correlations between Hydrodynamic Properties and Desulphation

This work evaluated the hydrodynamic properties of heparin hydrolysed at temperatures ranging from 40 °C to 80 °C in buffered acid and alkaline environments. The correlation between hydrodynamic parameters led to the conclusion that polymer conformational changes appeared to be minimal until chain d...

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Bibliographic Details
Main Authors: Aleksandra Maria Kozlowski, Vlad Dinu, Thomas MacCalman, Alan Mark Smith, Johannes Peter Roubroeks, Edwin Alexander Yates, Stephen Ernest Harding, Gordon Alistair Morris
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Polysaccharides
Subjects:
heparin desulphation
hydrodynamic properties
activity
Online Access:https://www.mdpi.com/2673-4176/4/2/7

Internet

https://www.mdpi.com/2673-4176/4/2/7

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