Mesenchymal Stem Cell Conditioned Medium Modulates Inflammation in Tenocytes: Complete Conditioned Medium Has Superior Therapeutic Efficacy than Its Extracellular Vesicle Fraction

Mesenchymal Stem Cell Conditioned Medium Modulates Inflammation in Tenocytes: Complete Conditioned Medium Has Superior Therapeutic Efficacy than Its Extracellular Vesicle Fraction

Tendinopathy, a prevalent overuse injury, lacks effective treatment options, leading to a significant impact on quality of life and socioeconomic burden. Mesenchymal stem/stromal cells (MSCs) and their secretome, including conditioned medium (CM) and extracellular vesicles (EVs), have shown promise...

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Bibliographic Details
Main Authors: Robert Soukup, Iris Gerner, Thomas Mohr, Sinan Gueltekin, Johannes Grillari, Florien Jenner
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
equine mesenchymal stem cells (MSC)
MSC secretome
MSC extracellular vesicles (EVs)
MSC protein fraction
cell-free therapy
tenocytes regeneration
Online Access:https://www.mdpi.com/1422-0067/24/13/10857

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https://www.mdpi.com/1422-0067/24/13/10857

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