Keratinocyte PIEZO1 modulates cutaneous mechanosensation

Keratinocyte PIEZO1 modulates cutaneous mechanosensation

Epidermal keratinocytes mediate touch sensation by detecting and encoding tactile information to sensory neurons. However, the specific mechanotransducers that enable keratinocytes to respond to mechanical stimulation are unknown. Here, we found that the mechanically-gated ion channel PIEZO1 is a ke...

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Bibliographic Details
Main Authors: Alexander R Mikesell, Olena Isaeva, Francie Moehring, Katelyn E Sadler, Anthony D Menzel, Cheryl L Stucky
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
keratinocyte
touch sensation
pain
Piezo1
mechanotransduction
Online Access:https://elifesciences.org/articles/65987

Internet

https://elifesciences.org/articles/65987

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