The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains

The cohesin ATPase cycle is mediated by specific conformational dynamics and interface plasticity of SMC1A and SMC3 ATPase domains

Summary: Cohesin is key to eukaryotic genome organization and acts throughout the cell cycle in an ATP-dependent manner. The mechanisms underlying cohesin ATPase activity are poorly understood. Here, we characterize distinct steps of the human cohesin ATPase cycle and show that the SMC1A and SMC3 AT...

Full description

Bibliographic Details
Main Authors: Marina Vitoria Gomes, Pauline Landwerlin, Marie-Laure Diebold-Durand, Tajith B. Shaik, Alexandre Durand, Edouard Troesch, Chantal Weber, Karl Brillet, Marianne Victoria Lemée, Christophe Decroos, Ludivine Dulac, Pierre Antony, Erwan Watrin, Eric Ennifar, Christelle Golzio, Christophe Romier
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724010076

Internet

http://www.sciencedirect.com/science/article/pii/S2211124724010076

Similar Items