Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

Molecular Determinants of Cancer Therapy Resistance to HDAC Inhibitor-Induced Autophagy

Histone deacetylation inhibitors (HDACi) offer high potential for future cancer therapy as they can re-establish the expression of epigenetically silenced cell death programs. HDACi-induced autophagy offers the possibility to counteract the frequently present apoptosis-resistance as well as stress c...

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Bibliographic Details
Main Authors: Maria Mrakovcic, Leopold F. Fröhlich
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cancers
Subjects:
histone deacetylase inhibitor
hdaci
drug resistance
autophagy
cell death
cancer
tumor
chemotherapy
radiotherapy
Online Access:https://www.mdpi.com/2072-6694/12/1/109

Internet

https://www.mdpi.com/2072-6694/12/1/109

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