Log D analysis using dynamic approach
Log D the logarithm (log10) of the distribution coefficient (D), is one of the important parameters used in Lipinski's rule to assess the druggability of a molecule in pharmaceutical formulations. The distribution of a molecule between a hydrophobic organic phase and an aqueous buffer phase is...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-12-01
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Series: | Biochemistry and Biophysics Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580818300839 |