Log D analysis using dynamic approach

Log D the logarithm (log10) of the distribution coefficient (D), is one of the important parameters used in Lipinski's rule to assess the druggability of a molecule in pharmaceutical formulations. The distribution of a molecule between a hydrophobic organic phase and an aqueous buffer phase is...

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Bibliographic Details
Main Authors: Ganeshkumar Krishnamoorthy, Prashanth Alluvada, Esayas Alemayehu, Shahul Hameed Mohammed Sherieff, Wasihun A. Addi, Timothy Kwa, Janarthanan Krishnamoorthy
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818300839