Pharmacogenetics of microRNAs and microRNAs biogenesis machinery in pediatric acute lymphoblastic leukemia.

Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated the relationship between genetic variation and treatment-related toxicity. H...

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Main Authors: Elixabet López-López, Ángela Gutiérrez-Camino, Maria Ángeles Piñán, José Sánchez-Toledo, Jose Javier Uriz, Javier Ballesteros, Purificación García-Miguel, Aurora Navajas, África García-Orad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3948785?pdf=render