Evaluation of The Relationship among The Levels of SIRT1 and SIRT3 with Oxidative Stress and DNA Fragmentation in Asthenoteratozoospermic Men

Evaluation of The Relationship among The Levels of SIRT1 and SIRT3 with Oxidative Stress and DNA Fragmentation in Asthenoteratozoospermic Men

Background: Reactive oxygen species (ROS) play a crucial role in etiology of DNA fragmentation and lipid peroxidationin sperm, leading to infertility in men. The silent information regulators SIRT1 and SIRT3 are members of thesirtuins protein family known to be involved in cancer genetics, aging and...

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Bibliographic Details
Main Authors: Abolfazl Nasiri, Asad Vaisi-Raygani, Zohreh Rahimi, Mitra Bakhtiari, Fariborz Bahrehmand, Amir Kiani, Hadi Mozafari, Tayebeh Pourmotabbed
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2021-04-01
Series:International Journal of Fertility and Sterility
Subjects:
dna fragmentation
infertility
oxidative stress
sirt1
sirt3
Online Access:https://www.ijfs.ir/article_46366_bead94d3c252105793ef9293c1707728.pdf

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https://www.ijfs.ir/article_46366_bead94d3c252105793ef9293c1707728.pdf

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