Regulation of IgE activity in inhalational tolerance via formation of IgG anti-IgE/IgE immune complexes

Abstract Background Allergic asthma is an inflammatory disorder of the airways that results from inappropriate production of IgE against harmless, environmental antigens. Sequestration of free IgE using humanized IgG anti-IgE is an effective therapy for asthma and other atopic disorders. However, th...

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Bibliographic Details
Main Authors: Sonali J. Bracken, Alexander J. Adami, Ektor Rafti, Craig M. Schramm, Adam P. Matson
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Clinical and Molecular Allergy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12948-018-0091-x