LncRNA X Inactive Specific Transcript Exerts a Protective Effect on High Glucose-Induced Podocytes by Promoting the Podocyte Autophagy via miR-30d-5p/BECN-1 Axis

Inhibiting podocyte autophagy promotes the development of diabetic nephropathy (DN). This study aims to explore the upstream regulatory mechanism of the autophagy-related gene BECN1 in high glucose (HG)-induced podocytes. C57BL/6 mice were treated with 50 mg/kg streptozotocin to construct a DN model...

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Bibliographic Details
Main Authors: Ying Cai, Sheng Chen, Xiaoli Jiang, Qiyuan Wu, Yong Xu, Fang Wang
Format: Article
Language:English
Published: Hindawi Limited 2023-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2023/3187846