Relative abundance data can misrepresent heritability of the microbiome

Relative abundance data can misrepresent heritability of the microbiome

Abstract Background Host genetics can shape microbiome composition, but to what extent it does, remains unclear. Like any other complex trait, this important question can be addressed by estimating the heritability (h 2 ) of the microbiome—the proportion of variance in the abundance in each taxon th...

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Bibliographic Details
Main Authors: Marjolein Bruijning, Julien F. Ayroles, Lucas P. Henry, Britt Koskella, Kyle M. Meyer, C. Jessica E. Metcalf
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Microbiome
Subjects:
Absolute abundance
Compositional data
Genetic variance
Host-microbe associations
Microbiota
Phenotypic variance
Online Access:https://doi.org/10.1186/s40168-023-01669-w

Internet

https://doi.org/10.1186/s40168-023-01669-w

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