Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats

Peripheral Interaction of Resolvin D1 and E1 with Opioid Receptor Antagonists for Antinociception in Inflammatory Pain in Rats

Antinociceptive pathways are activated in the periphery in inflammatory pain, for instance resolvins and opioid peptides. Resolvins are biosynthesized from omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid and docosahexaenoic acid. Resolvin D1 (RvD1) and resolvin E1 (RvE1) initiate t...

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Bibliographic Details
Main Authors: Beatrice Oehler, Milad Mohammadi, Cristina Perpina Viciano, Dagmar Hackel, Carsten Hoffmann, Alexander Brack, Heike L. Rittner
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
resolvin
opioid receptors
opioid peptides
transient receptor potential channels
inflammation
animals
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00242/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00242/full

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