Comprehensive plasma cytokine and chemokine profiling in prurigo nodularis reveals endotypes in Type 2 inflammation

Abstract Prurigo nodularis (PN) is a chronic inflammatory skin disease that is associated with variability in peripheral blood eosinophil levels and response to T-helper 2 targeted therapies (Th2). Our objective was to determine whether circulating immune profiles with respect to type 2 inflammation...

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Bibliographic Details
Main Authors: Hannah L. Cornman, Jaya Manjunath, Sriya V. Reddy, Jackson Adams, Ahmad Rajeh, Christeen Samuel, Aaron Bao, Ryan Zhao, Emily Z. Ma, Jason Shumsky, Thomas W. Pritchard, Brenda Umenita Imo, Alexander L. Kollhoff, Kevin K. Lee, Weiying Lu, Selina Yossef, Madan M. Kwatra, Shawn G. Kwatra
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58013-x