A Race against the Clock: A Case Report and Literature Review Concerning the Importance of ADAMTS13 Testing in Diagnosis and Management of Thrombotic Thrombocytopenic Purpura during Pregnancy

A Race against the Clock: A Case Report and Literature Review Concerning the Importance of ADAMTS13 Testing in Diagnosis and Management of Thrombotic Thrombocytopenic Purpura during Pregnancy

Thrombocytopenic purpura (TTP) is a rare, potentially fatal pathology characterized by microangiopathic thrombotic syndrome and caused by an acute protease deficiency of von Willebrand factor, ADAMTS13. Moreover, ADAMTS13 deficiency promotes microthrombosis led by the persistence of ultra-large VWF...

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Bibliographic Details
Main Authors: Melinda Ildiko Mitranovici, Lucian Pușcașiu, Ioan Emilian Oală, Izabella Petre, Marius Lucian Craina, Antonia Rebeka Mager, Kinga Vasile, Diana Maria Chiorean, Adrian-Horațiu Sabău, Sabin Gligore Turdean, Ovidiu Simion Cotoi
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Diagnostics
Subjects:
thrombotic thrombocytopenic purpura
von Willebrand factor protease
ADAMTS13
vascular microthrombosis
pregnancy
fetal–maternal mortality
Online Access:https://www.mdpi.com/2075-4418/12/7/1559

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https://www.mdpi.com/2075-4418/12/7/1559

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