Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection.

Association of IFNL3 rs12979860 and rs8099917 with biochemical predictors of interferon responsiveness in chronic hepatitis C virus infection.

BACKGROUND & AIMS:Genetic variations near the interferon lambda 3 gene (IFNL3, IL28B) are the most powerful predictors for sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV) infection, compared to other biochemical or histological baseline parameters. We evaluate...

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Bibliographic Details
Main Authors: Janett Fischer, Stephan Böhm, Tobias Müller, Heiko Witt, Christoph Sarrazin, Simone Susser, Pascal Migaud, Eckart Schott, Graeme Stewart, Annika Brodzinski, Balazs Fülöp, Florian van Bömmel, Jacob George, Thomas Berg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3812277?pdf=render

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http://europepmc.org/articles/PMC3812277?pdf=render

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