Purinergic signaling: A gatekeeper of blood-brain barrier permeation

Purinergic signaling: A gatekeeper of blood-brain barrier permeation

This review outlined evidence that purinergic signaling is involved in the modulation of blood-brain barrier (BBB) permeability. The functional and structural integrity of the BBB is critical for maintaining the homeostasis of the brain microenvironment. BBB integrity is maintained primarily by endo...

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Bibliographic Details
Main Authors: Yuemei Wang, Yuanbing Zhu, Junmeng Wang, Longcong Dong, Shuqing Liu, Sihui Li, Qiaofeng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
purinergic signaling
blood-brain barrier
endothelial cells
P2Y receptors
P2X receptors
P1 receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1112758/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1112758/full

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