Heparin releases newly synthesized cell surface-associated apolipoprotein E from HepG2 cells.

Heparin significantly increased the amount of newly synthesized apolipoprotein E (apoE) released by HepG2 cells. Culturing cells in the presence of 10 micrograms/ml of heparin for 2-6 days caused a 1.3-fold (day 2) to 3-fold (day 6) increase of extracellular apoE without affecting the total amount o...

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Bibliographic Details
Main Authors: M Lilly-Stauderman, TL Brown, A Balasubramaniam, JA Harmony
Format: Article
Language:English
Published: Elsevier 1993-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520407461