A Phase I Trial to Determine the Pharmacokinetics, Psychotropic Effects, and Safety Profile of a Novel Nanoparticle-Based Cannabinoid Spray for Oromucosal Delivery

A Phase I Trial to Determine the Pharmacokinetics, Psychotropic Effects, and Safety Profile of a Novel Nanoparticle-Based Cannabinoid Spray for Oromucosal Delivery

Introduction: A phase I, open-label clinical trial in healthy male subjects was conducted to assess the pharmacokinetic and safety profile of an oromucosal cannabinoid spray (AP701) containing a lipid-based nanoparticular drug formulation standardized to ∆-9-tetrahydrocannabinol (THC). Methods: Twel...

Full description

Bibliographic Details
Main Authors: Stefan Lorenzl, Franz Gottwald, Angelika Nistler, Laura Brehm, Renate Grötsch, Georg Haber, Christian Bremm, Christiane Weck, Carina Trummer, Werner Brand
Format: Article
Language:English
Published: Karger Publishers 2022-01-01
Series:Medical Cannabis and Cannabinoids
Subjects:
pharmacokinetics
safety
cannabinoids
oromucosal spray
nanoparticles
Online Access:https://www.karger.com/Article/FullText/521352

Internet

https://www.karger.com/Article/FullText/521352

Similar Items