STUDY OF THE EFFECT OF STRUCTURE ON OCTANOL-WATER DISTRIBUTION OF 6-HYDROXYPYRIMIDINE-4-(<i>3H</i>)-ONES DERIVATIVES
The results of an experimental study of the effect of structure of substituting groups and pH value on the partition coefficients in biphasic systems of n-octanol and water for a number of 2,5-substituted 6-hydroxypyrimidine-4-(3H)-ones are presented.
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-01-01
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| Series: | Разработка и регистрация лекарственных средств |
| Subjects: | |
| Online Access: | https://www.pharmjournal.ru/jour/article/view/426 |