Glycosylated Triterpenoids as Endosomal Escape Enhancers in Targeted Tumor Therapies
Protein-based targeted toxins play an increasingly important role in targeted tumor therapies. In spite of their high intrinsic toxicity, their efficacy in animal models is low. A major reason for this is the limited entry of the toxin into the cytosol of the target cell, which is required to mediat...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-03-01
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Series: | Biomedicines |
Subjects: | |
Online Access: | http://www.mdpi.com/2227-9059/5/2/14 |