Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells

Stimulation of β-adrenergic receptors plays a protective role via increased expression of RAF-1 and PDX-1 in hyperglycemic rat pancreatic islet (RIN-m5F) cells

Introduction : It is a widely held view that a progressive reduction of beta-cell mass occurs in the progression of diabetes. RAF-1 kinase and pancreas duodenal homeobox 1 (PDX-1) are major factors that promote survival of cells and maintain normal insulin functions. In this study we investigated th...

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Bibliographic Details
Main Authors: Sher Zaman Safi, Rajes Qvist, Gracie Ong, Hamed Karimian, Muhammad Imran, Ikram Shah
Format: Article
Language:English
Published: Termedia Publishing House 2016-12-01
Series:Archives of Medical Science
Subjects:
β-adrenergic receptors
v-raf-leukemia viral oncogene 1
pancreas duodenal homeobox 1
hyperglycemia
apoptosis
insulin
Online Access:https://www.termedia.pl/Stimulation-of-adrenergic-receptors-plays-a-protective-role-via-increased-expression-of-RAF-1-and-PDX-1-in-hyperglycemic-rat-pancreatic-islet-RIN-m5F-cells,19,28858,1,1.html

Internet

https://www.termedia.pl/Stimulation-of-adrenergic-receptors-plays-a-protective-role-via-increased-expression-of-RAF-1-and-PDX-1-in-hyperglycemic-rat-pancreatic-islet-RIN-m5F-cells,19,28858,1,1.html

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