In vivo label-free optical signatures of chemotherapy response in human pancreatic ductal adenocarcinoma patient-derived xenografts

In vivo label-free optical signatures of chemotherapy response in human pancreatic ductal adenocarcinoma patient-derived xenografts

Abstract Pancreatic cancer is a devastating disease often detected at later stages, necessitating swift and effective chemotherapy treatment. However, chemoresistance is common and its mechanisms are poorly understood. Here, label-free multi-modal nonlinear optical microscopy was applied to study mi...

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Bibliographic Details
Main Authors: Jaena Park, Janet E. Sorrells, Eric J. Chaney, Amro M. Abdelrahman, Jennifer A. Yonkus, Jennifer L. Leiting, Heidi Nelson, Jonathan J. Harrington, Edita Aksamitiene, Marina Marjanovic, Peter D. Groves, Colleen Bushell, Mark J. Truty, Stephen A. Boppart
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05368-y

Internet

https://doi.org/10.1038/s42003-023-05368-y

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